Abstract
INTRODUCTION: Spina bifida affects 0.5-1 in 1000 pregnancies in the United States. Imaging has played a major role in pregnancies complicated by spinal defects. Our goal was to directly compare ultrasounds and MRI obtained antenatally in the diagnosis and localization of fetal myelomeningocele and compare these to the postnatal outcomes of these infants. METHODS: A retrospective analysis of patients referred to the Fetal Care Center at the Cleveland Clinic from 2005-2017. Ultrasounds and MRIs were obtained within the Cleveland Clinic electronic medical record. Infants were followed up at an interdisciplinary myelomeningocele pediatrics clinic. RESULTS: MRI and US varied in correlation with physical exam at time of birth and surgery. While no differences were detected in demographics, pregnancy outcomes or pediatric outcomes, it was noted the majority of patients developed neurogenic bladders irrespective of lesion level. CONCLUSION: MRI is not superior to US in the diagnosis of MMC. Pregnancies complicated by MMC do not vary in morbidity and pediatric outcomes remain similar regardless of level of lesion. This data provides additional information for the counseling of patients when faced with this antenatal diagnosis.
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