Abstract
Prenatal and perinatal characteristics as possible risk factors for febrile seizures were reviewed by analysis of the data from the collaborative perinatal project of the National Institute of Neurological Disorders and Stroke at the Neuroepidemiology Branch, Bethesda, MD.
Highlights
Prenatal and perinatal characteristics as possible risk factors for febrile seizures were reviewed by analysis of the data from the collaborative perinatal project of the National Institute of Neurological Disorders and Stroke at the Neuroepidemiology Branch, Bethesda, MD
The authors indicate that several earlier reports have shown that abnormalities in perinatal histories were relatively frequent in children with febrile seizures but the studies were not controlled
Reported in 19 studies between 1933-1963 17% showed evidence of possible brain injury caused by trauna or anoxia as an antecedent of febrile seizures
Summary
History was the major factor identified as contributory to febrile seizure vulnerability. The authors indicate that several earlier reports have shown that abnormalities in perinatal histories were relatively frequent in children with febrile seizures but the studies were not controlled. The Editor is Professor of Neurology and Pediatrics at Northwestern University Medical School, Chicago, and is presently at Southern Illinois University School of Medicine, Springfield, Illinois, USA. Reported in 19 studies between 1933-1963 17% showed evidence of possible brain injury caused by trauna or anoxia as an antecedent of febrile seizures. Trauma or anoxia at birth was a frequent finding in the history of the febrile convulsive disorder and was implicated with equal frequency in patients with simple febrile seizures and those with complex febrile seizures. The authors indicate that some relationships not uncovered in the study of the total cohort of febrile seizures might emerge in an analysis of clinically defined subsets
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