Abstract
Urine δ-aminolevulinic acid (ALAU) excretion has previously been reported as being closely correlated with the clinical picture of lead poisoning. In the present investigation, rats were administered either zinc or lead or both. Zinc administration resulted in the reduction to near normal levels of ALAU excretion in lead-intoxicated rats. This effect occurred in the absence of any significant reduction in blood lead levels or any alleviation of the anemia of lead toxicity. The observations place considerable doubt on the validity of using ALAU screening tests as a means of determining lead exposure.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.