Abstract
Due to the emergence of increased level of antibiotic resistance among uropathogens, urinary tract infections or UTI became a severe menace to mankind affecting millions of people every year. At this context, the present study was designed to compare the antagonistic activity exhibited by Mimosa pudica and Moringa oleifera against UTI causing bacteria and the phytochemical constituents possessed by them. Various solvent extracts of the leaves of M. pudica and M. oleifera were prepared and evaluated for their antagonistic activities against urinary tract infection causing bacteria by agar well diffusion method. Also the phytochemical screening of these two plants was done qualitatively. The results of the antagonistic activity of M. pudica and M. oleifera revealed that the leaves of both the plants possess remarkable antagonistic properties against bacteria causing UTI. The phytochemical analysis revealed the presence of secondary metabolites such as flavonoids, saponins, steroids, tannins and coumarins. From the above study, it can be concluded that the leaves of M. pudica can be considered as a potential agent of antagonistic properties that can be used to develop novel drugs against bacteria that cause UTI.
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