Abstract
Sufficient experimental and clinical data are at hand to prove that the pituitary gland is related to carbohydrate metabolism. Goetsch, Cushing and Jacobson 1 noted that injections of posterior pituitary extract produced glycosuria, and Achard, Ribot and Binet 2 also found that injections of this extract caused glycosuria. The latter likewise noted that the hyperglycemia produced by intravenous glucose solutions was increased by the simultaneous injections of pituitary extract. It is logical, therefore, to study the effects of posterior pituitary extract and insulin on blood sugar. Burn 3 studied this problem, proving that the pituitary extract has a powerful antagonistic effect on the lowering of blood sugar produced by insulin. His conclusions, in part, are that subcutaneous injections of posterior pituitary extract given simultaneously with injections of insulin diminish or abolish the fall of sugar produced by the latter. The doses of pituitary extract used do not, when given alone,
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