Abstract

Repeated injections of taurine sharply reduce or abolish seizure activity induced by application of cobalt to the cerebral cortex. Within the limits of the experimental model of epilepsy used, the anti-epileptic action of this amino acid appear permanent. In parallel to the improvement in the epileptic signs, abnormalities in amino acid content of brain associated with the disorder, also disappear. The observations suggest that taurine stimulates certain biochemical processes in the CNS which aid in the recovery from cobalt induced epilepsy.

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