Abstract
Objective: The management of poor responders is a recurring dilemma for IVF programs. Currently, two alternative stimulation protocols are most commonly used in order to minimize suppression of follicular development in women with a history of poor response; the microdose GnRH agonist flare or the GnRH antagonist protocol. Patients who have undergone either one of the two protocols in an unsuccessful cycle, will sometimes be switched to a different protocol hoping for an improvement in the overall outcome. Only one study in the literature, with a small number of patients, compares the efficacy of these protocols, and show them to be equivalent in poor responders (Akman et al, 2001). Our study evaluates the findings when microdose GnRH agonist flare and antagonist protocols were used in the same patients in different cycles.
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