Abstract
AbstractStinging ants are now recognized as being of considerable public health significance in both temperate and tropical regions. Many species of ants produce venoms that contain powerful algogens and these secretions may cause severe systemic reactions as well. Venoms of fire ants (Solenopsis species) are fortified with unique necrotoxins that produce conspicuous lesions at the sting sites. The diverse pharmacological properties of ant venoms are mirrored by the varied biological activities that these secretions possess.The poison gland products of selected ant venoms are cytotoxic and hemolytic against a variety of red blood cells. Some venoms are potently bactericidal and fungicidal against a variety of microorganisms. Venoms of Solenopsis and Monomorium species are highly effective contact insecticides and repellents as well. In addition, these secretions can also inhibit enzymes (e.g., Na+ ATPase), uncouple oxidative phosphorylation, reduce mitochondrial respiration, and release histamine from mas...
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