Abstract
Another step towards improving oncofertility counselling of young women with Hodgkin's lymphoma.
Highlights
Possible chemotherapy-induced premature ovarian insufficiency is of great concern for female premenopausal patients with cancer
Done within the RATHL trial (NCT00678327), biomarkers of ovarian function during and up to 3 years after chemotherapy were assessed in women younger than 45 years at the time of diagnosis
Despite a few limitations, including the small sample size of the antimüllerian hormone analysis, of those who were treated with BEACOPP, and the lack of collection of participant information from the main RATHL cohort that could have had a potential effect on outcomes, this study provides more precise information than previous reports to counsel women with Hodgkin’s lymphoma on gonadal damage induced by ABVD, AVD, or BEACOPP
Summary
Possible chemotherapy-induced premature ovarian insufficiency is of great concern for female premenopausal patients with cancer.
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