Another Disordered Chameleon: The Micro-Exon Gene 14 Protein from Schistosomiasis

Abstract

If knowledge regarding proteins were restricted to what is presented in contemporary biochemistry textbooks, one would think that all proteins adopt the three-dimensional structures encoded by their amino-acid sequences, and that each structure in turn provides the basis for each protein’s function. This sequence-to-structure-to-function hypothesis for protein structure-function relationships is highly ingrained in contemporary thinking about proteins.