Another depot neuroleptic: pipothiazine

Abstract

Pipothiazine palmitate (Piportil Depot) is a piperidine phenothiazine derivative, the seventh long-acting injectable neuroleptic to be marketed in the UK.1 Although new here, it has been used for more than a decade in other countries.2,3 After injection pipothiazine acts for about 4 weeks (range 2–8 weeks), longer than other injectable neuroleptics.