Abstract

Reported is a case of cervical atypical mycobacterial infection treated with an extended course of clarithromycin in a 23-month-old child who developed sensorineural hearing loss. While no subjective change in hearing was reported, hearing loss was identified through audiologic ototoxicity monitoring. Audiometric changes encompassing frequency specific threshold shifts and changes in distortion product otoacoustic emissions are shown during the use of and following discontinuation of clarithromycin. Observed hearing loss resolved following termination of clarithromycin. This is believed to be the first report of a pediatric patient on clarithromycin developing reversible sensorineural hearing loss with documented serial audiometric changes.

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