Abstract
Abstract Anomalous panleukocytic granulation is described in the peripheral blood, bone marrow and spleen of a 3 year old girl. Myeloid leukocytes showed giant peroxidase and Sudan Black B-positive granules. Lymphocyte corpuscles were positive in the periodic acid-Schiff test. Deviations in the structure and segmentation of the neutrophil nuclei were observed. Increase of gamma globulins and decrease of lipoproteins were found in the blood serum. Hepatosplenomegaly, psychomotor underdevelopment, respiratory tract infections, roentgenologic changes of bones, lungs and heart were also found. The parents were first cousins, and anomalous corpuscles were seen in the father’s lymphocytes. At necropsy diffuse or focal infiltration of the organs by lymphoid, plasma and reticular cells suggested a systemic condition.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
