Abstract

Abstract The polarographic behavior of ethinamate and methylpentynol carbamate was studied. Both drugs developed anodic waves in a supporting electrolyte composed of 1M sodium hydroxide and methanol (9 + 1). The relation between the limiting current and the concentration was rectilinear over the range 2.5 X 10-5-2.5 X 10-4M for both drugs. The characteristics of the waves were studied, and a model of the electrode reaction was suggested. The proposed method was successfully applied to the determination of the 2 drugs in their dosage forms, and the results were in agreement with those obtained with published methods.

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