Abstract
Chitosan is an attractive material for biomedical applications. A novel approach for the anodic electrodeposition of chitosan–AgNP composites using in situ coordination with copper ions is proposed in this work. The surface and cross-section morphology of the obtained coating with varying concentrations of AgNPs were evaluated by SEM, and surface functional groups were analyzed with FT-IR spectroscopy. The mechanism of the formation of the coating based on the chelation of Cu(II) ions with chitosan was discussed. The antibacterial activity of the coatings towards Staphylococcus epidermidis ATCC 35984/RP62A bacteria was analyzed using the live–dead approach. The presented results indicate that the obtained chitosan–AgNP-based films possess some limited anti-biofilm-forming properties and exhibit moderate antibacterial efficiency at high AgNP loads.
Highlights
Nowadays, natural polymers are of significant importance due to their unique properties and possibility of production from renewable sources
The results confirmed that spherical Ag nanoparticles were formed during the synthesis
The size of AgNPs was determined based on the dydynamic light scattering (DLS) measurement that revealed their average diameter of 28 ± 4.3 nm and 31 ± 3.3 nm, which indicated their monodispersity
Summary
Natural polymers are of significant importance due to their unique properties and possibility of production from renewable sources. Chitosan (CS) is one of the most promising polysaccharide biopolymers with high practical potential due to its non-toxic nature, biocompatibility, antimicrobial activity, film-forming properties, relative chemical, and mechanical stability [1,2]. These properties make CS coatings useful for biomedical, packaging, pharmaceutical, and water-treatment applications [2,3,4,5,6]. Their usage in the biomedical sector remains dominant. The exact mechanism of the antibacterial activity of CS is not yet fully understood, but it is presumably connected to its polycationic structure in acidic aqueous solutions
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