Abstract

Aim: Baldness is one of the most common cosmetic problems of our time. It negatively affects self-esteem and mood, which causes a deterioration in the quality of life. For years, scientists have been trying to discover a remedy to stop hair loss. The aim of this paper is to review the current reports about action of polyphenols contained in annurca apples on baldness available on PubMed and Google Scholar, including in vitro, animal, and clinical studies. Methods: The research method was a critical analysis of scientific articles available in the Pubmed and Google Schoolar databases. The team reviewed content from 2004 to 2023. paying special attention to the latest news. By systematizing and verifying the content, 24 most reliable publications were selected and the work was based on them. Results: Current treatments have many disadvantages, ranging from low effectiveness to burdensome side effects. Therefore, it is worth looking into the achievements of natural medicine. A promising discovery seems to be an extract from the substances contained in the Annurca apple extract (AAE). This fruit holds high levels of polyphenols, including procyanidin B-2 (PCB2), which has been linked to hair growth promotion. Conclusions: In this work, we checked the effectiveness of Annurca apple supplementation in the treatment and prevention of baldness in scientific sources. Available research shows that including annurca apple extract in the diet is a promising alternative to previously known baldness treatment methods. Further research and meta-analyses are needed to clearly assess the effectiveness of the preparations. However, it is a promising alternative to previously known treatment methods for baldness.

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