Abstract

AbstractHerein we report a method for the synthesis of 2‐aryl thiochromenones via a sulfuration of 2’‐chlorochalcones. The chalcones could be prepared in advance or in situ obtained from 2’‐chloroacetophenones and aromatic aldehydes. The conditions were tolerant of functionalities including chloro, fluoro, methylthio, phenoxy, and trifluoromethyl groups. 2‐Heteroaryl thiochromenones could also be obtained in moderate yields. Our method appears to be a simple, general tactic to afford 2‐aryl thiochromenones from commercial starting materials.

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