Annular elastolytic giant cell granuloma

Abstract

A 49-year-old woman had large annular lesions with raised erythematous borders and atrophic, hypopigmented central regions on her neck, trunk, and proximal upper extremities. Examination of a biopsy specimen demonstrated a granulomatous infiltrate in the upper dermis that surrounded areas lacking elastic fibers; elastic fibers were present within the multinucleated giant cells. The clinical presentation and pathologic findings were consistent with a diagnosis of annular elastolytic giant cell granuloma (AEGCG). The clinical description and pathologic differential diagnosis of AEGCG are reviewed.