Abstract

Objective:to evaluate the efficacy of quality of life questionnaires St. George Respiratory Questionnaire and Chronic Obstructive Pulmonary Disease Assessment Test in patients with chronic obstructive pulmonary disease based on correlation and agreement analyses, and identify the most effective tool to assess their quality of life.Method:cross-sectional cohort study with patients hospitalized in a Spanish hospital for exacerbation of chronic obstructive pulmonary disease. Health-related quality of life was assessed with both questionnaires. The correlation and the agreement between the questionnaires were analyzed, as well as the internal consistency. Associations were established between the clinical variables and the results of the questionnaire.Results:one hundred and fifty-six patients participated in the study. The scales had a correlation and agreement between them and high internal consistency. A higher sensitivity of the Chronic Obstructive Pulmonary Disease Assessment Test was observed for the presence of cough and expectoration.Conclusion:the questionnaires have similar reliability and validity to measure the quality of life in patients with acute chronic obstructive pulmonary disease, and the Chronic Obstructive Pulmonary Disease Assessment Test is more sensitive to detect cough and expectoration and requires a shorter time to be completed.

Highlights

  • Chronic obstructive pulmonary disease (COPD) is a common disease and 80 million people suffer from the severe or moderate form of this disease[1-2]

  • A total of 466 patients were admitted for exacerbation of COPD in the HUGC, where 310 were excluded due to physical or mental disabilities (n = 66), terminal condition (n = 85), previous inclusion (n = 66), existence of language barrier (n = 9), or patients who had the criteria but rejected the invitation to share in the study (n = 84)

  • The existence of correlation between the results of the two questionnaires has been valued by several researchers[13] and even a correlation of the St. George Respiratory Questionnaire (SGRQ) spheres with the total Chronic Obstructive Pulmonary Disease Assessment Test (CAT) result has been reported[26], but no study correlated all questions with the SGRQ spheres

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Summary

Introduction

Chronic obstructive pulmonary disease (COPD) is a common disease and 80 million people suffer from the severe or moderate form of this disease[1-2]. COPD is an avoidable and treatable disease[1]. The test to diagnose COPD is spirometry (forced expiratory volume ratio in the first second (FEV1)/forced vital capacity (FVC) less than 70 after bronchodilation)(1). Continuous reduction in lung function is a result of the progression of the disease. This situation worsens during periods of exacerbation, which happens once or twice a year. The treatment requires hospitalization to control the symptoms, in a large number of patients[4], implying a high cost for the management of the pathology[5]. The exacerbations accelerate the continuous reduction of lung function, reducing the Health Related Quality of Life (HRQL) of patients

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