Animal Model for Diabetes Co-existing with Metabolic Syndrome

Abstract

Metabolic syndrome includes diverse disorders together with truncal obesity, dyslipidemia, high blood pressure, and hyperglycemia. The occurrence of metabolic syndrome is growing globally. The unfavorable results of metabolic syndrome have brought on research efforts to broaden new interventions to reduce the weight of the healthcare system. Because of its multifactorial nature, it may be hard to pick out the best experimental version that high-quality represents the pathophysiology of human metabolic syndrome. Many animal models have evolved and been studied to clarify the molecular mechanisms and useful modifications associated with metabolic sicknesses. Properly characterized and clinically applicable experimental models are taken into consideration as crucial tools for testing new pills and information on their molecular foundation, their pathogenesis, and mechanism of movement. In this review, we collate and discuss the various animal models of metabolic syndrome and the suitability of diabetes co-existing with metabolic syndrome animal models for research also be discussed to provide the readers with a comprehensive overview of the selection of the best animal models to meet their research purpose. Keyword:Animal model, Metabolic syndrome, High fat diet, Rat