Abstract

Animal arterivirus infections.

Highlights

  • BioMed Research International significant concern about cross species transmission of some of these arteriviruses following xenotransplantation

  • It is obvious that transplantation of humans with tissues from simian hemorrhagic fever virus (SHFV)-infected baboons or porcine reproductive and respiratory syndrome virus (PRRSV)-infected pigs would result in transfer of a considerable amount of these viruses, which could result in selection of a variant(s) that can replicate in humans

  • In conjunction with advances in PRRSV molecular virology, reverse genetics and immunology, more and more attention is being directed to development of safe and efficacious vaccines against PRRSV

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Summary

Introduction

BioMed Research International significant concern about cross species transmission of some of these arteriviruses following xenotransplantation. R. Rowland,[3] Hanchun Yang,[4] and Dongwan Yoo[5] The arteriviruses (Family Arteriviridae, Genus Arterivirus) include an interesting group of enveloped positive stranded RNA viruses that infect domestic and wild animals and they share a strikingly similar genome organization and replication strategy to that of coronaviruses, but differ considerably in their genetic complexity and virion architecture.

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