Abstract
The resilience of ancient DNA (aDNA) in bone gives rise to the preservation of synthetic DNA with bioinorganic materials such as calcium phosphate (CaP). Accelerated aging experiments at elevated temperature and humidity displayed a positive effect of co-precipitated, crystalline dicalcium phosphate on the stability of synthetic DNA in contrast to amorphous CaP. Quantitative PXRD in combination with SEM and EDX measurements revealed distinct CaP phase transformations of calcium phosphate dihydrate (brushite) to anhydrous dicalcium phosphate (monetite) influencing DNA stability.
Highlights
This is an Accepted Manuscript, which has been through the Royal Society of Chemistry peer review process and has been accepted for publication
In no event shall the Royal Society of Chemistry be held responsible for any errors or omissions in this Accepted Manuscript or any consequences arising from the use of any information it contains
The resilience of ancient DNA in bone gives rise to the preservation of synthetic DNA with bioinorganic materials such as calcium phosphate (CaP)
Summary
This article can be cited before page numbers have been issued, to do this please use: P. This is an Accepted Manuscript, which has been through the Royal Society of Chemistry peer review process and has been accepted for publication. Accepted Manuscripts are published online shortly after acceptance, before technical editing, formatting and proof reading. Using this free service, authors can make their results available to the community, in citable form, before we publish the edited article. Authors can make their results available to the community, in citable form, before we publish the edited article We will replace this Accepted Manuscript with the edited and formatted Advance Article as soon as it is available. Antkowiak,a Julian Koch,a Przemyslaw Rzepka,a Bichlien H.
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