Anhidrosis and nonhealing painless leg ulcer with osteomyelitis in a young boy

Abstract

The hereditary sensory and autonomic neuropathies (HSAN) are a group of very rare genetic disorders, characterized by prominent sensory as well as autonomic neuropathy without any motor involvement. Five main groups (type-I through type-V) of HSAN do exist. We report here a case of a chronic nonhealing leg ulcer in a young boy associated with anhidrosis, diagnosed as HSAN type-IV with osteomyelitis, for its rarity, and to emphasize the importance of considering this entity in the differential diagnoses of chronic nonhealing ulcers in the pediatric population.