Abstract
Cardiovascular disease is the leading cause of mortality in the UK with ischaemic heart disease and heart failure being the main contributors. The renin-angiotensin aldosterone system has an essential role in cardiovascular pathophysiology by increasing preload, afterload and left ventricular workload. Angiotensin converting enzyme inhibitor therapy is a first-line therapy in this patient population except for those who are intolerant of angiotensin converting enzyme inhibitors. Angiotensin receptor blockers are deemed as a safe alternative while achieving the same clinical benefit. Common adverse effects are hypovolaemia, hyperkalemia and renal dysfunction. The nursing role involves cardiovascular assessment, monitoring for adverse effects and patient education.
Published Version
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