Abstract
Cardiovascular disease is the leading cause of mortality in the UK with ischaemic heart disease and heart failure being the main contributors. The renin-angiotensin aldosterone system has an essential role in cardiovascular pathophysiology by increasing preload, afterload and left ventricular workload. Angiotensin converting enzyme inhibitor therapy is a first-line therapy in this patient population except for those who are intolerant of angiotensin converting enzyme inhibitors. Angiotensin receptor blockers are deemed as a safe alternative while achieving the same clinical benefit. Common adverse effects are hypovolaemia, hyperkalemia and renal dysfunction. The nursing role involves cardiovascular assessment, monitoring for adverse effects and patient education.
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