Abstract
New Zealand White rabbits were used as a model of autologous venous bypass grafting. A section of jugular vein was sutured into the divided common carotid artery. The animals were euthanized one month after surgery. At that time histopathology showed myointimal thickening of the graft segments. Angiotensin II receptor assays showed that the AT1 receptor was present in the grafts, concentrated in the intima. These localized receptors were shown to be similar to the prototypic vascular AT1 receptor through the use of the specific antagonist DuP 753.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Biochemical and Biophysical Research Communications
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
