Abstract
Foeniculum vulgare Mill and Coriandrum sativum L. are very popular spices in Indian kitchens. The present study was an attempt to evaluate the angiotensin converting enzyme (ACE) inhibition and antioxidant activity of the standardized oils of F. vulgare and C. sativum by an UV method using hippuryl-L-histidyl-L-leucine (HHL) as substrate. Standardization of the oils and identification of the chemical-markers (linalool and anethole) present in them was performed through HPLC and GC-MS. Coriander oil showed the higher ACE inhibition with an IC50 value of 34.8 ± 2.3 μg/mL, than fennel oil with an IC50 value of 40.7 ± 3.5 μg/mL. Both oils showed strong DPPH radical scavenging activity. This finding suggests that coriander and fennel oils can be potential leads for the management of hypertension as an ACE inhibitor.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
