Angiomyomatous hamartoma: Unusual presentation of a rare entity

Abstract

Angiomyomatous hamartoma (AMH) is a rare benign vascular growth primarily affecting inguinal and femoral lymph nodes (LNs). Here, we present a unique case of AMH manifesting as a submental neck mass, a location seldom reported in literature. A 20-year-old male presented with a palpable midline neck mass adjacent to the hyoid bone. Ultrasonography suggested a partially cystic lesion, prompting consideration of thyroglossal duct cyst or necrotic lymph node. Fine-needle aspiration (FNA) hinted at a benign cystic lesion, potentially a thyroglossal duct cyst. Surgical excision via the Sistrunk approach revealed no cyst but characteristic features of AMH upon histopathological examination. This case underscores the importance of considering AMH in the differential diagnosis of subcutaneous nodules in unusual locations and highlights the role of surgical excision for both diagnosis and treatment. Our findings expand the understanding of AMH's clinical presentation and emphasize the necessity of a comprehensive differential diagnosis approach for nodal lesions.