Abstract

Angiomyofibroblastoma is a rare,usually small benign mesenchymal tumor that occurs mainly but not exclusively in the vulval region of premenopausal women. Patients often present with non specific symptoms. It is a well circumscribed lesion that clinically is often thought to represent a Bartholin's gland cyst. Diagnostic confusion often arise between angiomyofibroblastoma and other tumors arising in the vulval region like aggressive angiomyxoma and cellular angiofibroma because of overlapping histological features. Differentiating between angiomyofibroblastoma and cellular angiofibroma is not of clinical significance.Aggressive angiomyxoma is a more infiltrative lesion that has a high propensity for local recurrence. Immunohistochemistry is not of much help in distinguishing these entities. Sincere efforts should be made to differentiate angiomyofibroblastoma from aggressive angiomyxoma, which has a potential to metastasize or recur.

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