Angiomatosis, a newly recognized disease in Atlantic bottlenose dolphins (Tursiops truncatus) from the Gulf of Mexico.

Abstract

A new disease, angiomatosis, was recognized in 25 of 54 (46.3%) Atlantic bottlenose dolphins (Tursiops truncatus) necropsied after being stranded along the Texas Gulf coast during 1991-1996. Angiomatosis was first recognized by the authors in 1992 and has increased in incidence and severity, affecting 100% of juveniles and adults. This disease is characterized by proliferation of small, thick-walled blood vessels diffusely throughout the lungs, without inflammation, exudation, or alveolar hemorrhage. The vascular proliferation also occurs in lung-associated and other visceral lymph nodes. Hemangiomas frequently occur in affected lymph nodes and occasionally in the lungs. The vascular proliferation reduces airspace and may occlude small airways. Angiomatosis appears to be a broad-field defect of vascular endothelium. Although this process appears to be an increasingly important factor in the morbidity of T. truncatus, its etiology has not been determined.