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Abstract
IntroductionAngioimmunoblastic T-cell lymphoma is a rare form of tumor of the lymph nodes or lymphoid tissue. In this report we describe an unusual presentation of angioimmunoblastic T-cell lymphoma consisting of giant kidneys with no nephrotic syndrome.Case presentationA 46-year-old Arabic man from Gaza was hospitalized in our ward due to abdominal pain and a weight loss of 20 kg during the preceding two months. The results of the physical examination and laboratory tests raised the possibility of neoplastic disease. A computerized tomographic scan of the abdomen showed huge kidneys, and a kidney biopsy showed infiltration by lymphocytes and eosinophils. The genetic examination revealed T-cell lymphoma. Diagnosis was made by a lymph node biopsy, which shows typical findings of angioimmunoblastic T-cell lymphoma.ConclusionsAngioimmunoblastic T-cell lymphoma can present with huge kidneys without nephrotic syndrome.
Highlights
Angioimmunoblastic T-cell lymphoma is a rare form of tumor of the lymph nodes or lymphoid tissue
In this report we describe an unusual presentation of angioimmunoblastic T-cell lymphoma consisting of giant kidneys with no nephrotic syndrome
We report the case of a man who sought medical advice due to weight loss and abdominal pain, and whose unusual presentation of angioimmunoblastic T-cell lymphoma consisted of giant kidneys with no nephrotic syndrome
Summary
Angioimmunoblastic T-cell lymphoma is rare, occurring in only 1% of all cases of lymphoma. We report the case of a man who sought medical advice due to weight loss and abdominal pain, and whose unusual presentation of angioimmunoblastic T-cell lymphoma consisted of giant kidneys with no nephrotic syndrome. Case presentation A 46-year-old Arabic man from Gaza was hospitalized in our ward due to abdominal pain and a weight loss of 20 kg during the preceding two months. His medical history did not contribute any useful information for the diagnosis and he denied fever or night sweats. The constellation of eosinophilia, hyperglobulinemia, generalized lymphadenopathy, giant kidneys and the findings in the lymph node biopsy were consistent with the diagnosis of angioimmunoblastic T-cell lymphoma. Repeated laboratory tests showed decreased globulin levels, and his blood count showed no elevation in the eosinophil level
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