Angioimmunoblastic T cell lymphoma co-occurring with gamma heavy chain disease and plasma cell dyscrasia – a case report

Abstract

Background: Gamma heavy chain disease (GHCD) is a rare B-cell neoplasm that produces a truncated heavy chain that lacks light chain-binding sites.1 Angioimmunoblastic T-cell lymphoma (AITL) is associated with EBV driven lymphoproliferative disease,2 and EBV-independent plasma clonal cell expansion,3 but concurrence with both has not been described.