Angina Pektoris Hastalarında B-Tipi Natriüretik Peptit ve Kalsiyum Skoru

Abstract

Objective: The purpose of this study is to look into the relationship between coronary artery disease evaluated with multislice computed tomography (MSCT) findings and B-type natriuretic peptide (BNP) and calcium score (CaS). Material and Method: The study included 83 patients who were administered to our center and who had asymptomatic and stable angina pectoris. Blood samples were collected for BNP testing, and the Abbott AxSYM System kit was used for measurements. Calcium scoring was performed on each of the four main coronary arteries, and the total “Agatston” score was calculated for each patient by summing up the results. MSCT angiograms were studied at the three-dimensional operating base. Results: Coronary artery disease (CAD) was found in 51 (61.4%) patients, while the coronary arteries of 32 (38.6%) patients were deemed normal. Single-vessel involvement was detected in 17 (20.5%) patients, two-vessel involvement in 18 (21.7%) patients, and three-vessel involvement in 16 (19.3%) patients. While patients with CAD had a median BNP of 33.9 (0–834), those without CAD had a median of 19.2 (0–185), which was statistically significant (p=0.011). Furthermore, there was a positive correlation between the number of vessels involved and BNP (r = 0.364, p=0.001). BNP levels were found to be significantly higher in hypertensive patients (p=0.008). The CaS and BNP median of the group with three-vessel involvement were significantly higher (p < 0.001 and p=0.007, respectively). Conclusion: As a result, high CaS and BNP levels were discovered to be a marker for the presence and severity of CAD.