Abstract

Characteristic epileptic seizures and EEG abnormalities are reported in three siblings with Angelman syndrome from the Kansai University Otokoyoma Hospital, Kyoto; and the Nagasaki University School of Medicine, Japan.

Highlights

  • Contrary to recent concern regarding possible adverse effects of phenobarbital on cognitive function, this study shows no significant effects on reaction time and attention

  • ANGELMAN SYNDROME AND EPILEPSY Characteristic epileptic seizures and EEG abnormalities are reported in three siblings with Angelman syndrome from the Kansai University Otokoyoma Hospital, Kyoto; and the Nagasaki University School of Medicine, Japan

  • Angelman syndrome is characterized by brachycephaly, microcephaly, mental retardation, jerky puppet-like movements of

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Summary

Introduction

Contrary to recent concern regarding possible adverse effects of phenobarbital on cognitive function, this study shows no significant effects on reaction time and attention. The authors do not recommend CBZ in preference to other AEDs. ANGELMAN SYNDROME AND EPILEPSY Characteristic epileptic seizures and EEG abnormalities are reported in three siblings with Angelman syndrome from the Kansai University Otokoyoma Hospital, Kyoto; and the Nagasaki University School of Medicine, Japan.

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Conclusion
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