AneuRisk65: A dataset of three-dimensional cerebral vascular geometries

Laura M Sangalli,Simone Vantini,Piercesare Secchi

doi:10.1214/14-ejs938

Abstract

We describe the AneuRisk65 data, obtained from image reconstruction of three-dimensional cerebral angiographies. This dataset was collected for the study of the aneurysmal pathology, within the AneuRisk Project. It includes the geometrical reconstructions of one of the main cerebral vessels, the Inner Carotid Artery, described in terms of the vessel centreline and of the vessel radius profile. We briefly illustrate the data derivation and processing, explaining various aspects that are of interest for this applied problem, while also discussing the peculiarities and critical issues concerning the definition of phase and amplitude variabilities for these three-dimensional functional data.

Highlights

The AneuRisk65 data have been collected within the AneuRisk project,1 a scientific endeavour that aimed at investigating the role of vessel morphology, blood fluid dynamics and biomechanical properties of the vascular wall, on the pathogenesis of cerebral aneurysms
An increasing data warehouse concerning aneurysm pathology can be accessed from the AneuRisk Web Repository http://ecm2.mathcs.emory.edu/aneurisk managed by Emory University and Orobix
Possible explanations that have been discussed in the medical literature focus on interactions between the biomechanical properties of artery walls and hemodynamic factors, such as wall shear stress and pressure; the hemodynamics is in turn strictly dependent on vascular geometry

Summary

The AneuRisk project and the AneuRisk65 data

The AneuRisk data have been collected within the AneuRisk project, a scientific endeavour that aimed at investigating the role of vessel morphology, blood fluid dynamics and biomechanical properties of the vascular wall, on the pathogenesis of cerebral aneurysms. Detailed descriptions of the project’s aims can be found at the AneuRisk webpage http://mox.polimi.it/it/progetti/aneurisk/, where the AneuRisk data can be downloaded These data include the image reconstructions of one of the main cerebral vessels, the Inner Carotid Artery (ICA), described in terms. An increasing data warehouse concerning aneurysm pathology can be accessed from the AneuRisk Web Repository http://ecm2.mathcs.emory.edu/aneurisk managed by Emory University and Orobix. These data include the full three-dimensional reconstructions of the ICA walls, and of the connecting arteries, as well as data concerning hemodynamical quantities, such as wall shear stress and pressure, obtained via computational fluid dynamics in the real subject-specific ICA geometries (see Passerini et al, 2012)

Problem and data

Data processing

Findings

A first look at phase variability in the AneuRisk65 data