Abstract

SummaryHeterozygous white diploid strains of yeast of which one parent is a particular red adenine‐requiring haploid strain often throw a large number of red sectors when they are plated on nutrient agar. It has been shown by genetic analysis and other tests that many of the white spore cultures from one such heterozygote are disomic haploids of constitution n+1 =AD1/ad1. By an extension of the analysis to the red spore cultures from the same heterozygote, it has been shown that some of these are also disomic haploids of constitution n+1 =ad1/ad1. It is concluded that the red haploid strain involved in the heterozygote is a trisomic haploid of constitution n+2 =ad1/ad1/ad1. The genetical significance of the diploid → aneuploid → diploid cycle in a fast multiplying unicellular organism is discussed.

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