Abstract

Two hundred and thirty-five patients of both sexes (123 male, 112 female) aged 18-54 yr, weighing 35-62 kg underwent repair of tetralogy of Fallot from January 1996 to July 2009 in Fuwai hospital. Direct BP, ECG, CVP, SpO2, naso-pharyngeal temperature and TEE were continuously monitored during operation. Anesthesia was induced with midazolam and/or etomidate, fentanyl and pipecurenium and maintained with isoflurane/sevoflurane inhalation and intermittent iv boluses of fentanyl and pipecuronium. The total amount of fentanyl administered ranged from 30-50 ug/kg. Cardiac function was supported and hemodynamic stability was maintained with vasoactive and inotropic drugs. Measures were taken to strengthen blood conservation and respiratory function support. Seven patients (2.9%) needed urgent CPB during operation because of serious cyanotic spells. Perfusion-induced lung injury occurred in 18 patients (7.6%). Circulation was assisted by ECMO in 2 patients (0.9%). Three patients (1.3%) died of serious low cardiac output and perfusion-induced lung injury. Key words: Tetralogy of Fallot ; Cardiac surgical procedures ; Adult ; Anesthesia

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