Anesthetic effects of sevoflurane combined with remifentanil on thoracoscopic lobectomy under general anaesthesia

Abstract

Objective To investigate the anesthetic effects of sevoflurane combined with remifentanil on thoracoscopic lobectomy under general anesthesia. Methods From May 2016 to October 2017, 128 patients with thoracoscopic lobectomy under general anesthesia in our hospital were selected, and they were divided into two groups by random number table, with 64 cases in each group. The patients in the control group were given anesthesia with sevoflurane, while the patients in the observation group were given anesthesia with sevoflurane and remifentanil. The mean arterial pressure (MAP) and heart rate (HR) levels before anesthesia induction, at the beginning of operation, at 30 min after the beginning of operation, at tracheal extubation time were compared between the two groups. The awakening time, tracheal extubation time, pain, cough and agitation at extubation were compared between the two groups. Results The MAP and HR levels of the observation group were lower than those in the control group at the tracheal extubation time (P<0.05). The awakening time and tracheal extubation time of the observation group were shorter than those of control group, and the numerical rating scale (NRS) score was lower than that of the control group (P<0.05). The incidences of cough and agitation in the observation group were lower than those in the control group (P<0.05). Conclusions Sevoflurane combined with remifentanil in thoracoscopic lobectomy under general anesthesia can effectively improve the MAP and HR levels at the tracheal extubation time, shorten the awakening time and tracheal extubation time, reduce the pain and the incidences of cough and agitation. Key words: General anesthesia; Thoracoscopic lobectomy; Sevoflurane; Remifentanil