Abstract
Objective To compare the anestheticl effects of inhaling sevoflurane by different induction methods.Method 90 patients undergoing endotracheal intubation for elective operation from January 2012 to December 2012 in the Department of General Surgery were randomly divided into a vital capacity technique group (Group Ⅰ,n=30),a tidal volume technique group (Group Ⅱ,n=30),and an increasing concentration group (Group Ⅲ,n=30).8％ of sevoflurane and 4L/min oxygen flow were used for inducing anesthesia (for Group Ⅲ,the sevoflurane concentration was gradually increased by 1％ every 25 s).1.5-2.0 mg · kg-1 · h-1 propofol and 1-2 μ g · kg-1 · h 1 remifentanil were used for continuous anesthesia.Diastolic blood pressure (DBP),systolic blood pressure (SBP),mean arterial pressure (MAP),heart rate (HR),pluse oxygen saturation (SpO2),muscle relaxant effects,and adverse effects were observed before and after the induction.Results There were no statistical differences in all the indexes before anethesia induction(T1) between the three groups.The disappearing times of eyelash reflex were (83.2 ± 23.18) s,(110.3 ± 26.740 s,and (142.6 ± 25.14) s in Group Ⅰ,Group Ⅱ,and Group Ⅲ,respectively,with stitistical differences between each two groups.The DBP,SBP,MAP,and HR of the three groups decreased after anethesia (compared to T1,P＜0.05),but there were no statistical differences between the three group at the same time (P＞0.05).The SpO2 of the three groups increased after anethesia(compared to T1,P＜0.05),but with no statistical difference between the three groups at the same time (P＞0.05).Patients in the three groups showed similar restored times of muscular relaxation.There was no statistical differences in the incidence of adverse reaction between the three groups (10.0％ for Group Ⅰ,6.7％ for both Group Ⅱ and Group Ⅲ,x 2=0.310,P＞0.05).Conclusions There were no statistical differences in anesthetic effect and between the three induction methods of inhaled sevoflurane.The induction time of vital capacity technique was the shortest. Key words: Sevoflurane; Inhalation anesthesia; Induction methods
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