Anesthesia in a Patient with Stiff Person Syndrome: About A Case

Abstract

Stiff person syndrome, characterized by stiffness in the muscles of the torso and extremities and painful episodic spasms, is a rare autoimmune neurological disease. Here we present successful endotracheal intubation. A 46- year-old man underwent surgery with ASA-III classification due to necrosectomy following fasciitis necrotizing. After induction of anesthesia using fentanil propofol and rocuronium, tracheal intubation proceeded easily without neuromuscular blockade. Anesthesia was maintained with isoflurane and an O 2 /air mixture. After an uneventful intraoperative period, the patient was extubated. The evolution was marked by death following a septic shock. Although the mechanism is unclear, neuromuscular blockers and volatile anesthetics can cause prolonged hypotonia in patients with stiff-man syndrome.