Anesthesia in a child with severe restrictive pulmonary dysfunction caused by chronic graft- versus-host disease

Abstract

Chronic graft- versus-host disease (GVHD) affects 30% to 50% of allogenic bone marrow transplant (BMT) recipients surviving the acute phase. We describe the clinical features and the anesthetic management of a child with a systemic form of GVHD resulting in severe restrictive pulmonary dysfunction.