Anesthesia Effect of Propofol Nanoinjection Combined with Nerve Block

Abstract

Anesthesia for upper limb surgery is commonly used in clinical practice. At present, the traditional method uses anatomical localization for nerve block, which can result incomplete local block and reduced anesthetic effect. Instead, ultrasound-guided nerve block can help clinicians intuitively grasp structure of patient tissues and provide a real-time display of needle penetration. Propofol is the most commonly used intravenous anesthetic in the world, but its use is still limited. In order to improve the limitations of this drug, a propofol nanoemulsion was developed and used in combination with a lower brachial plexus block. In this study, 100 patients were randomly divided into two groups, 50 in each group. The propofol nanoinjection for nerve block was used in the experimental group and ketamine was used in the control group. The quality of the operation, respiratory inhibition/asphyxia, recovery time, OPS score, agitation score, and complications were compared between the two groups. There was no significant difference in blood loss between the two groups (P > 0 05). The experimental results showed that the lower brachial plexus block and propofol nanoemulsion provided a better analgesic effect than ketamine and propofol nanoemulsion in the operation.