Abstract
Andrographis paniculata is widely cultivated and its importance as a medicinal plant is growing up with stronger reports in support of its multifarious therapeutic uses. Taking great concern of the useful benefits of the plant, it can be advocated as a safe, highly important medicinal plant for mankind. This herb contains a large number of chemical constituents, mainly lactones, diterpenoids, diterpene glycosides, flavonoids and flavonoid glycosides. It has multiple pharmacological properties such as antibacterial, hepatoprotective activity, anti-cancer, antitumor, hypoglycemic, immunomodulatory and hypotensive activities. The earlier and current status of therapeutic usage, phytochemistry, pharmacological activity and toxicity profile research on Andrographis paniculata has been described in this review as to bridge the gap required for the coming research opportunities in future. It also emphasizes at compiling vast pharmacological applications to make the potential image of Andrographis paniculata as a multipurpose medicinal agent. The extracts and metabolites of this plant did not show any kind of significant acute toxicity in experimental animals.
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