Abstract

Background: The first case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified in Wuhan, China, in late 2019, the epicenter of the COVID-19 outbreak. In India on 30.01.2020 and in Andhra Pradesh on 12.03.2020 first case was reported. The Case Fatality Rate among diagnosed cases is generally about 2% to 3% but varies by country.Objective: To estimate the Case Fatality Rate (CFR) in Andhra Pradesh during the pandemic in different phases. Methods: All the secondary data were collected either from the covid19india website or github website or Indian government websites or Andhra Pradesh State government website or media quoting the government announcements 30.01.2020 to 16.08.2020. The case fatality rate was estimated as per the Methods for Estimating the Case Fatality Ratio for a Novel, Emerging Infectious Disease. Statistical Analysis: Data were entered and analyzed using SPSS V24. Descriptive statistics were represented with percentages; mean with SD. K-means clustering analysis was applied to make the classification of Andhra Pradesh Districts based on the magnitude of CFR.Results: In the pre-lockdown phase, the CFR of Andhra Pradesh was 0.00%, Uttarandhra, Central Andhra & Rayalaseema was Nil, and South Andhra it was ranging from Nil-0.00%,In lockdown phase, the CFR Andhra Pradesh was ranging from 1.34- 42.31%, Uttarandhra - Nil -5.56%, Central Andhra - Nil-100.00%, South Andhra - 0.00-66.67%, and Rayalaseema - Nil-100.00%.In post-lockdown phase, the CFR Andhra Pradesh was ranging from 0.99- 2.50%, Uttarandhra - 0.59 -4.55%, Central Andhra - 0.82-14.33%, South Andhra - 1.05-2.30%, and Rayalaseema - 0.37-8.07%.Conclusions: The Case Fatality Rate of confirmed cases of COVID-19 in Andhra Pradesh and its districts was a downward trend except Prakasam district.

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