Abstract

High-resolution esophageal manometry (HREM) is a technique to determine the function of esophageal musculature and integrity of esophagogastric junction. Conventionally, the HREM study is done in the supine position using ten swallows of 5 ml water each. Apart from this mandatory testing, ancillary testing and maneuvers are undertaken to elicit detailed physiological information. These include multiple rapid swallows, rapid drink tests, testing in the upright position with solid swallows, and pharmacological testing. The present review highlights these techniques and their clinical utility.

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