Abstract
The Han Chinese are the largest ethnic group in the world, and their origins, development, and expansion are complex. Many genetic studies have shown that Han Chinese can be divided into two distinct groups: northern Han Chinese and southern Han Chinese. The genetic history of the southern Han Chinese has been well studied. However, the genetic history of the northern Han Chinese is still obscure. In order to gain insight into the genetic history of the northern Han Chinese, 89 human remains were sampled from the Hengbei site which is located in the Central Plain and dates back to a key transitional period during the rise of the Han Chinese (approximately 3,000 years ago). We used 64 authentic mtDNA data obtained in this study, 27 Y chromosome SNP data profiles from previously studied Hengbei samples, and genetic datasets of the current Chinese populations and two ancient northern Chinese populations to analyze the relationship between the ancient people of Hengbei and present-day northern Han Chinese. We used a wide range of population genetic analyses, including principal component analyses, shared mtDNA haplotype analyses, and geographic mapping of maternal genetic distances. The results show that the ancient people of Hengbei bore a strong genetic resemblance to present-day northern Han Chinese and were genetically distinct from other present-day Chinese populations and two ancient populations. These findings suggest that the genetic structure of northern Han Chinese was already shaped 3,000 years ago in the Central Plain area.
Highlights
The Han Chinese are the largest ethnic group in the world and have a current population of a staggering 1.3 billion individuals [1]
During the Han Dynasty (260 BC-220 AD), the Huaxia ethnic group developed into a tribe known as the Han Chinese [3]. Because of their advanced agriculture and technology, this group migrated northward into regions inhabited by many ancient northern ethnic groups that were most likely Altaic in origin [4]
Independent replicates were made for each sample, and four samples yielded amplified mitochondrial DNA (mtDNA) HVR-I sequences that could not be reproduced, the controls used during DNA extraction and PCR were always negative
Summary
The Han Chinese are the largest ethnic group in the world and have a current population of a staggering 1.3 billion individuals [1]. The generally accepted view is that the Han Chinese can trace their origins to the Huaxia ethnic group, which formed. Tracing the Genetic History of the Northern Han Chinese design, data collection and analysis, decision to publish, or preparation of the manuscript
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