Abstract

Ancepsone A, a new sesterterpene with 13,19-epoxycheilanthane skeleton, i.e (17Z)-13,19-epoxycheilanth-1,17-diene-2-ol-3-one (1), together with eight known natural products (2 ∼ 9) were isolated from Aleuritopteris anceps. The structure of the new compound was established by means of 1D and 2D NMR, MS, and single-crystal X-ray diffraction methods. All compounds were isolated from A. anceps for the first time. Ancepsone A and the isolated flavonoids can moderately inhibit the proliferation of cancer cells.

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