Abstract

Abstract Lowering intraocular pressure (IOP) has been central to glaucoma care for over a century. Minimally invasive glaucoma surgical (MIGS) devices are able to exploit different aspects of aqueous outflow to reduce IOP. Increasing aqueous humour outflow may be achieved either through facilitating the existing pathways of Schlemm’s canal and the suprachoroidal space or to bypass the normal angle anatomy to create a full thickness fistula into the subconjunctival space. A complete understanding of angle anatomy and outflow pathways is important to develop new treatment strategies, improve current ones and better target the right operation for particular glaucoma subtypes.

Highlights

  • Invasive glaucoma surgery (MIGS) encompasses a group of procedures aiming to lower intraocular pressure (IOP) with reduced surgical times, more rapid postoperative recovery and a better safety profile compared with traditional filtration surgery

  • Because of the importance of the anterior chamber angle in the pathogenesis of glaucomatous damage, an understanding of angle anatomy and aqueous outflow structures is critical to surgical planning and device selection for particular glaucoma subtypes

  • Aqueous draining through the trabecular outflow system will traverse the trabecular meshwork, through the juxtacanalicular connective tissue, into Schlemm’s canal and the collecting channels, and into the aqueous veins which drain into the episcleral venous system

Read more

Summary

Introduction

Invasive glaucoma surgery (MIGS) encompasses a group of procedures aiming to lower intraocular pressure (IOP) with reduced surgical times, more rapid postoperative recovery and a better safety profile compared with traditional filtration surgery. Increasing aqueous humour (AH) outflow may be achieved either through facilitating the existing pathways of Schlemm’s canal and the suprachoroidal space or to bypass the normal angle anatomy to create a full thickness fistula into the subconjunctival space. Because of the importance of the anterior chamber angle in the pathogenesis of glaucomatous damage, an understanding of angle anatomy and aqueous outflow structures is critical to surgical planning and device selection for particular glaucoma subtypes. This chapter reviews the clinically relevant anatomy and functionality of the outflow apparatus in the human eye

Aqueous Humour Outflow
Lam University of Toronto, Toronto, Ontario, Canada
Trabecular Meshwork
Schlemm’s Canal
Uveoscleral Outflow
Physiological Characteristics of Unconventional Outflow
Conjunctival Lymphatic System
Conclusions
Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.