Abstract
The perception of pain requires the transmission of an impulse from the periphery to the brain via neural elements. Multiple synapses take place along this route and at these junctions there may be augmentation or attenuation of the pain signal. This review will highlight the three-dimensional understanding of human anatomy relevant to the pain practitioner. It will discuss the autonomic nervous system and specific locations of ganglia that may be amenable to neural blockade. The somatic nervous system will also be discussed in detail, including regions amenable to neural blockade. An understanding of spinal anatomy is also paramount for the pain practitioner. This synthesis of anatomic descriptions and computerenhanced images offers the reader a complete guide for safe and successful performance of regional anesthesia.
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