Anatomy-based drug dosing strategies for surgical patients

Abstract

Introduction: Anatomy-based drug dosing strategies have emerged as a personalized approach to medication administration in surgical patients. In a sample of 150 patients who had major abdominal surgery, the purpose of this research was to assess the efficacy of this strategy. Methods: The anatomy-based dosage group and the control group were separated into two groups of patients. In the anatomy-based dosing group, medication doses were calculated based on individual body composition and organ function, while in the control group, medication doses were calculated based on standard weight-based dosing. The primary outcomes evaluated were the incidence of adverse drug reactions, pain scores, and time to postoperative recovery. Results: When compared to the control group's rate of adverse medication responses (30%), the incidence in the anatomy-based dosage group was much lower (14.3%). With a mean score of 3.8 compared to 4.4 in the control group, pain levels were also considerably lower in the anatomy-based dosage group. The mean postoperative recovery time was 8.2 days for the anatomy-based dosage group and 8.5 days for the control group, which is comparable between the two groups.