Abstract

BACKGROUND: There is a major debate in Alzheimer’s disease (AD) research about the role of neurofibrillary tangles (NFT) and senile plaques (SP), as well as their main molecular counterparts – tau and beta amyloid proteins – in the pathogenesis of the disease. In this sense, anatomo-clinical studies are of special interest, since they can ultimately determine which neuropathological lesion is more closely related to the cognitive deficits found in the disease […] Anatomo-clinical correlation study in Alzheimer’s disease (abstract)

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